Single-Cell Genomics

Computational and systems biologist Aviv Regev—MIT biology professor; Broad Institute core member and chair of faculty; Howard Hughes Medical Institute Investigator; and cofounder of the Human Cell Atlas initiative—studies how complex molecular circuits function in cells and between cells in tissues. The Regev lab invents experimental methods and associated computational algorithms, motivated by machine learning, that allow inference even in the context of the vast space of biological possibilities. Her lab has pioneered foundational experimental and computational methods in single-cell genomics, working toward greater understanding of the function of cells and tissues in health and disease, including autoimmune disease, inflammation, and cancer.